(주)비케이인스트루먼트

CHENOMX

NMR Metabolomics Software

대사체 연구를 위한 NMR 데이터 분석 처리 소프트웨어

Chenomx NMR 분석 소프트웨어는 Reference Libraries와 함께 작동하여 바이오 유체뿐만 아니라 식음료, 혼합물에서 대사물을 정확하게 식별하고 정량화 합니다.

The Chenomx Library

The Chenomx Spectral Reference Libraries are developed from thousands of reference spectra obtained through NMR analysis and used for identification and comparison purposes. The Reference Libraries are available from pH 4 through 9 and NMR field strengths from 400 MHz through 800 MHz.

Additional Reference Libraries have been created from the Human Metabolome Database (HMDB.ca) and are also available for download (Chenomx cannot certify these entries, but they can be used for ID purposes).

NMR Analysis Services

Chenomx NMR Analysis Services accurately identify and quantify metabolites in mixtures including depleted growth media, food and beverage, as well as bio-fluids.

We have partnered with a certified life science laboratory for sample preparation, and with an establish NMR instrument centre for data acquisition. Chenomx's experienced chemists utilize the software to perform the analysis of the mixtures.

Quality Assurance / Reporting

Analysis Services provide routine workflow that meets high quality standards. Each analysis is passed through a rigorous peer review from spectrum analysis, to assignment and quantification. Chenomx spreadsheet reports reveal concentrations of the measured metabolites in a tabular format.

1. Cell Culture

Metabolite analysis has proven to be an invaluable tool in observing and understanding the metabolic phenotype of cells in culture. In large bioreactor conditions, there are many challenges such as optimizing growth media, growth feeding strategies, and other engineering parameters that are vital not only for the growth of the cells but for the production of your products. With Chenomx's Profiling technology, getting reliable and quantitative data is key to overcoming many of these challenges.

2.Food And Nutrition

From essential amino acids to various sugars and other important components of food such as antioxidants, quantitative measurements of nutritional content of food is key to understanding the differences between food products. Understanding diet related diseases or growth factors, and their correlation to food intake is vital in our strive for better health. Earlier nutritional intervention can possibly prevent the onset of diseases that may require pharmaceutical aid in the future.

3.Drug Metabolism

As drug development costs skyrocket, it is ever so vital to fully understand your drug targets. Metabolomics can be a critical tool in drug discovery. From early detection of toxicity to mechanisms of action at a cellular level, positively identifying and quantifying metabolites in relevant biofluids can bridge the gap of understanding of your compounds. From preclinical to clinical stages of drug development pipeline, extra quantitative metabolite data will add real value to your drug submissions. Chenomx has years of experience with serum, plasma, urine, CSF, saliva, tissues, and cell based models.

4.Biomarker Discovery

Discovering new biomarkers has been a goal for clinical researchers to understand disease mechanisms and aid in the treatment of these diseases. Not only does NMR offer an analytical method to encompass a wide range of molecule types, but coupled with Chenomx technology, this technique becomes even more valuable as identification and quantification of the components in the samples are discovered. Chenomx has years of experience designing experiments, building diagnostic models, and validating them with clinical trial data.

[BKI] Chenomx Catalog.pdf